Ceporex Injection Data Sheet

Presentation
Ceporex Injection is an oily suspension of sodium cefalexin equivalent to 18% w/v cefalexin Ph.Eur.

Uses
Ceporex Injection is indicated for antibiotic therapy in cattle, cats and dogs. Cefalexin is a broad spectrum cephalosporin antibiotic with bactericidal activity against a wide range of Gram-positive and Gram-negative bacteria.
The following micro-organisms have been shown to be sensitive to cefalexin in vitro:

Staphylococcus spp. (including penicillin-resistant strains)

Streptococcus spp.	Actinomyces bovis
Corynebacterium spp.	Haemophilus spp.
Pasteurella spp.	Erysipelothrix rhusiopathiae
Escherichia coli	Clostridium spp.
Proteus spp.	Salmonella spp.
Micrococcus spp.	Fusobacterium spp.
Moraxella spp.	Peptostreptococcus spp.
Actinobacillus lignieresi	Peptococcus spp.

When susceptible organisms are present, Ceporex Injection is indicated in the treatment of infections of the respiratory tract, urogenital tract, the skin and localised infections in soft tissues in dogs and cats. In dogs it may also be effective in the treatment of the gastrointestinal tract.
Trials have shown Ceporex Injection to be of particular value in treating the following:
Cattle: Metritis, foot infections, wounds and abscesses and in the treatment of septicaemic mastitis to supplement intramammary therapy.

Dosage and administration
In the presence of water hydrolysis of cefalexin occurs. It is important, therefore, that a dry syringe is used when extracting suspension for injection to avoid contaminating the remaining contents of the vial with drops of water.
Before withdrawal of a dose the vial should be shaken to re-suspend the contents.

Dogs and cats
The recommended dose is 10 mg/kg once daily for up to 5 days. Any variation should be at the prescribing veterinary surgeons discretion, e.g. in severe or acute conditions. The following is intended as a guide:

Animal	Weight	Dose Volume
Cats: up to	4.5kg	0.25ml
Dogs: Small	5-9.0kg	0.25–0.5 ml
medium	9.0kg-27.0 kg	0.5–1.5 ml
large	27.0-54.0 kg	1.5–3.0 ml

Ceporex Injection may be administered by either the subcutaneous or intramuscular route. After administration massage the injection site. Ceporex Injection is not suitable for intravenous or intrathecal administration.

Large animals

Species	Dose rate	Dose Volume
Cattle	7 mg/kg	1ml/25kg

Ceporex Injection should be administered by the intramuscular route. It is not suitable for intravenous administration.
As with other antibiotics which are excreted mainly by the kidneys, unnecessary accumulation may occur in the body when renal function is impaired. In cases of known renal insufficiency the dose should be reduced.

Contra-indications, warnings, etc
Hypersensitivity to cefalexin is rare. However, Ceporex Injection should not be administered to animals which are known to be hypersensitive to cefalexin.

Pharmaceutical precautions
Protect from light. Do not store above 30°C.
Shake well before use. 
After withdrawal of the first dose, use the product within 28 days. When the container is broached for the first time, use the in-use shelf life which is specified on the packaging to calculate the date on which any remaining product should be discarded. This discard date should be written in the space provided on the label. Discard unused material.

Disposal
Dispose of used packaging in the household refuse. Unused product should be returned to the veterinary surgeon. Do not mix with any other veterinary product.

Legal category
POM-V

Packaging Quantities
Multidose vials 100 ml.

Further information