Panacur 2.5% Oral Suspension Data Sheet
Presentation
A 2.5% oral suspension of Fenbendazole as a ready to administer oral anthelmintic for cattle and sheep.
1ml contains 25mg active ingredient Fenbendazole.
Uses
A broad spectrum anthelmintic for the treatment of cattle and sheep infected with mature and developing immature forms of gastro-intestinal nematodes and lungworms. Panacur also has an ovicidal effect on nematode eggs.
Cattle
For the treatment of cattle infected with:
Ostertagia spp. | Cooperia spp. |
Trichostrongylus spp. | Nematodirus spp. |
Haemonchus spp. | Oesophagostomum spp. |
Bunostomum spp. | Strongyloides spp. |
Trichuris spp. | Dictyocaulus viviparus |
Panacur is usually effective against inhibited larvae of Ostertagia spp. and against Moniezia spp. of tapeworm.
Sheep
For the treatment of sheep infected with benzimidazole susceptible:
Ostertagia spp. | Haemonchus spp. |
Trichostrongylus spp. | Nematodirus spp. |
Cooperia spp. | Oesophagostomum spp. |
Chabertia spp. | Bunostomum spp. |
Strongyloides spp. | Dictyocaulus filaria. |
Panacur is usually effective against Moniezia spp. of tapeworm and may have useful but variable efficacy against Trichuris spp.
Dosage and administration
No dietary control is required before or after treatment.
Cattle
Administer orally 3 ml per 10 kg bodyweight. (= 7.5 mg fenbendazole/kg bodyweight).
Practical dosage recommendations:
50 kg | 15 ml |
100 kg | 30 ml |
150 kg | 45 ml |
200 kg | 60 ml |
250 kg | 75 ml |
300 kg | 90 ml |
350 kg | 105 ml |
Above 350 kg, an extra 15 ml are required for each additional 50 kg bodyweight.
Sheep
Administer orally 1 ml per 5 kg bodyweight. (= 5 mg fenbendazole/kg bodyweight)
Practical dosage recommendations:
Up to 15 kg | 3 ml |
16 to 25 kg | 5 ml |
26 to 35 kg | 7 ml |
36 to 50 kg | 10 ml |
51 to 65 kg | 13 ml |
66 to 75 kg | 15 ml |
Above 75 kg, an extra 2 ml are required for each additional 10 kg bodyweight.
The product is best administered to sheep with the Panacur Automatic Drencher but other standard dosing guns or drenching equipment may be used.
To ensure administration of a correct dose, body weight should be determined as accurately as possible; accuracy of the dosing device should be checked. Do not mix with other products.
Contra-indications, warnings, etc.
Intensive use or misuse of anthelmintics can give rise to resistance. To reduce this risk, dosing programmes should be discussed with your veterinary surgeon.
Care should be taken to avoid the following practices because they increase the risk of development of resistance and could ultimately result in ineffective therapy:
- Too frequent and repeated use of anthelmintics from the same class, over an extended period of time.
- Underdosing, which may be due to underestimation of body weight, misadministration of the product, or lack of calibration of the dosing device (if any).
Suspected clinical cases of resistance to anthelmintics should be further investigated using appropriate tests (e.g. Faecal Egg Count Reduction Test). Where the results of the test(s) strongly suggest resistance to a particular anthelmintic, an anthelmintic belonging to another pharmacological class and having a different mode of action should be used.
Resistance to benzimidazoles (which includes fenbendazole) has been reported in Teladorsagia, Haemonchus, Cooperia and Trichostrongylus species in small ruminants in a number of countries, including the EU. Therefore the use of this product should be based on local (regional, farm) epidemiological information about susceptibility of nematodes and recommendations on how to limit further selection for resistance to anthelmintics.
Fenbendazole belongs to the benzimidazole (1-BZ) class of anthelmintics.
Withdrawal periods
Animals must not be slaughtered for human consumption during treatment. Cattle may be slaughtered for human consumption only after 12 days from last treatment. Sheep may be slaughtered for human consumption only after 15 days from last treatment.
Milk for human consumption must not be taken during treatment.
Milk for human consumption may be taken from cows only after 5 days from last treatment.
Milk for human consumption may be taken from sheep only after 7 days from the last treatment.
Operator warnings
Direct contact with the skin should be kept to a minimum. Wear suitable protective clothing including impermeable rubber gloves. Wash hands after use.
For animal treatment only. Keep out of reach and sight of children.
Pharmaceutical precautions
Protect from frost. Do not freeze. Shake container before use. Keep container in its outer carton.
Disposal warnings
Dispose of any unused product or empty containers in accordance with any guidance from your local waste regulation authority. DANGEROUS to aquatic life. Do not contaminate ponds, waterways or ditches with the product or used containers.
Legal category
POM-VPS To be supplied only on veterinary prescription.
Package quantities
250 ml, 1, 2 and 10 litre multidose containers.
Further information
Nil.
Marketing authorisation number
Vm 01708/4429
