Panacur Equine Oral Paste 18.75% w/w Data Sheet

Dosage and Administration
It is recommended that horses and ponies are routinely wormed with a single dose of this product every 6 to 8 weeks. In Late Winter or Spring, mass emergence of encysted mucosal small redworm from the horse’s gut can cause parasitic diarrhoea, mild recurring colic, weight and appetite loss and weakness.
To avoid this, it is recommended that horses are administered the 5-day Panacur treatment in the Autumn (ideally late October/November) and again in the Spring (ideally in February). All new horses whose worming history is unknown should also be administered the 5-day Panacur treatment.
Pregnant mares and young foals may also be safely treated with Panacur at the recommended dosage levels.

Routine treatment
One syringe per 600 kg bodyweight as a single dose.
Administer the paste orally by squeezing onto the back of the horse’s tongue. Assess bodyweight as accurately as possible before calculating the dosage. The use of a ‘weigh band’ is recommended. It is not necessary to withhold feed before or after treatment.

Practical dosage recommendations

Increased dosing for specific infections

For the control of encysted small redworm and migrating large redworm larvae, administer one syringe per 600 kg bodyweight daily for 5 consecutive days.
For the control of diarrhoea caused by Strongyloides westeri, in 2-3 week-old suckling foals, administer one syringe per 90 kg bodyweight on a single occasion.
Studies have indicated that inhibited 3rd stage small strongyle larvae represent 50% of the total larval population in the horse.
Panacur has been used extensively for the treatment of worm infestations in exotic animal species. For further information on suggested dose rates, please contact the Veterinary Adviser of the company.

Contra-indications, warnings etc.
General warnings
Care should be taken to avoid the following practices because they increase the risk of development of resistance and could ultimately result in ineffective therapy:
  -  Too frequent and repeated use of anthelmintics from the same class, over an extended period of time.
  -  Underdosing, which may be due to underestimation of body weight, misadministration of the product, or lack of calibration of the dosing device (if any).

Suspected clinical cases of resistance to anthelmintics should be further investigated using appropriate tests (e.g. Faecal Egg Count Reduction Test). Where the results of the test(s) strongly suggest resistance to a particular anthelmintic, an anthelmintic belonging to another pharmacological class and having a different mode of action should be used.

Resistance to fenbendazole has been reported in cyathostomes in horses. Therefore the use of this product should be based on local (regional, farm) epidemiological information about susceptibility of nematodes and recommendations on how to limit further selection for resistance to anthelmintics.

User warnings
Direct contact with skin should be kept to a minimum. Wear impermeable rubber gloves while administering the product. Wash hands after use.

Disposal warnings
Dangerous to fish and aquatic life. Do not contaminate ponds, waterways or ditches with the product or used container.
Dispose of any unused product and empty containers in accordance with guidance from your local waste regulation authority.

Withdrawal periods
Not to be used in horses intended for human consumption.
Treated horses may never be slaughtered for human consumption.
The horse must have been declared as not intended for human consumption under national horse passport legislation.
For animal treatment only. Keep out of reach and sight of children.

Pharmaceutical Precautions
Do not store above 25°C. Protect from direct sunlight. Keep syringe in outer carton.