Bovilis® Bovivac® S Suspension for injection for cattle

Vaccine

Cattle

For the active immunisation of cattle against Salmonella dublin and Salmonella typhimurium, and to reduce Salmonella typhimurium infections in the face of an outbreak.

veterinary product by MSD Animal Healthveterinary product by MSD Animal Health

Presentation

Suspension for injection

Active ingredients

Inactivated cells of Salmonella dublin, strain S342/70 (1 x 109 cells/ml) and inactivated cells of Salmonella typhimurium, strain S341/70 (1 x 109 cells/ml).

Target species

Cattle.

Indications for use

For the active immunisation of cattle in order to induce serological and colostral antibody production against Salmonella Dublin and Salmonella typhimurium and in the face of an outbreak to reduce Salmonella typhimurium infections when used under field conditions as part of an overall herd management programme. This product may also contribute to reducing S. typhimurium contamination of the environment.

Withdrawal periods

Cattle – milk 0 hours, meat 0 days

Packaging

Polyethylene multidose bottles (50 ml) with rubber stoppers sealed with an aluminium crimp cap.

Legal category

POM-V

Frequently Asked Questions

What does Bovilis Bovivac S provide protection against?

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For the active immunisation of cattle in order to induce serological and colostral antibody production against Salmonella dublin and Salmonella typhimurium and in the face of an outbreak to reduce Salmonella typhimurium infections when used under field conditions as part of an overall herd management programme.
This product may also contribute to reducing S. typhimurium contamination of the environment.

What is the vaccination protocol for Bovilis Bovivac S?

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Vaccination dosage
Calves up to 6 months of age: 2 ml
Adult cattle: 5 ml

Route and method of administration
Subcutaneous injection preferably in the loose skin on the side of the neck, observing aseptic precautions.

Primary vaccination course
Where diagnosis of salmonellosis caused by S. dublin and/or S. typhimurium has been confirmed, all at risk adult cattle, including lactating cows, dry cows, heifers, barren cows and in-contact bulls (but excluding any with overt clinical signs of salmonellosis), should receive two 5 ml injections separated by an interval of 21 days.

For pregnant cows, this primary vaccination course can be given irrespective of the reproductive status. Any pregnant cows that have not calved within 8 weeks of the second dose of vaccine should receive a further 5 ml dose of Bovilis Bovivac S 3-4 weeks pre-calving.

Healthy calves from approximately 3 weeks of age may also be given a primary vaccination course. Calves should be given two 2 ml injections separated by an interval of 14 to 21 days.
All stock showing overt clinical signs of salmonellosis at the time of the initial vaccination programme should receive appropriate treatment and be fully vaccinated once they have recovered. Any unvaccinated stock must be managed separately to vaccinated stock, with no contact between the groups. Hygiene precautions must be instituted, where possible, to prevent transfer of infection from one group to another.

Re-vaccination scheme
All cattle vaccinated with the primary vaccination course of Bovilis Bovivac S should receive a 5 ml injection at least two weeks prior to each period of risk or at intervals of not more than 12 months thereafter.
As part of an overall herd management programme, for pregnant cattle, it is advised that for each subsequent pregnancy, in order to maintain a sufficient level of active immunisation to reduce S. dublin and S. typhimurium infections under field conditions, a single injection of 5 ml should be administered approximately 3-4 weeks before calving.

Can Bovilis Bovivac S be used at time of service or during pregnancy?

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The effect of Bovilis Bovivac S administered around service/insemination has not been studied.
Limited laboratory and field data suggest that vaccination with Bovilis Bovivac S has no adverse effect on pregnancy and calving.
When vaccinating animals, stress should be avoided, particularly during pregnancy.

What are the storage requirement for Bovilis Bovivac S?

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Store in a refrigerator (2 ⁰C – 8 ⁰C). Do not freeze. Protect from light.

What is the shelf life of Bovilis Bovivac S once broached?

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The shelf life of Bovilis Bovivac S once broached is 10 hours.
Partially used containers must be discarded at the end of each day’s operation.

What is the withdrawal period following the use of Bovilis Bovivac S?

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The withdrawal period following Bovilis Bovivac S is zero days.

Product images are representations of packaging and may not accurately reflect the current packaging available in the GB marketplace.

Date of preparation: August 2025

Further information is available from the SPC, datasheet or package leaflet. 
Advice should be sought from the medicine prescriber. 
Prescription decisions are for the person issuing the prescription alone. 
Use Medicines Responsibly.