What you should know about feline leukaemia virus    

There is no cure for FeLV infection. REDUCING THE RISK OF EXPOSURE and ENSURING ANY AT-RISK CATS ARE VACCINATED are the best ways to manage it.

Feline leukaemia virus (or FeLV) is an important cause of severe and often fatal disease in cats. Like other viruses, FeLV is effectively a tiny packet of genetic information and can only reproduce by infecting living cells, in this case of the cat. Based on the name, you might think that FeLV only causes blood cancer, like leukaemia in humans.  Although the virus can indeed cause leukaemia, it can also cause other cancers and also suppress the immune system leading to an increased susceptibility to many other infections, often with fatal consequences.

Many cats have lifestyles which place them at risk of infection with FeLV. This includes many young cats and kittens, cats that go outdoors, and cats that live in households with other cats that might carry the virus. Infection with FeLV in kittens and younger cats presents the greatest risk of individuals becoming persistently infected. Eighty-five percent of persistently infected cats die within three years of diagnosis.

FeLV is spread to healthy kittens and cats during close contact with infected individuals. Virus is spread in saliva, nasal secretions, urine, faeces and blood but survives outside the body only for a very short period. Mutual grooming or bite wounds tend to be the primary way cats become infected however something as simple as shared food or water dishes can also be sources of infection. Kittens can get the virus from infected mothers while still in the womb or through nursing.

Once the virus has infected a cat, it multiplies and enters the blood. Depending on how effective a cat’s immune system is in fighting the virus, the infection can take several courses. In some cats, the virus is successfully fought off. In others, it hides in body tissues but does not cause immediate signs of disease. In other cats, it spreads throughout the body and causes serious illness.

Typically the younger the cat, the more likely that persistent infection and severe disease will result with fatal consequences

Many cats will have no signs of illness initially, but their health will gradually become worse over weeks, months, or even years. Many cats show a large variety of signs that are not very specific, including poor coat condition, skin and respiratory infections, eye problems and weakness, in addition to a host of other issues.

Your vet can determine if a cat is infected with FeLV by performing a simple blood test that identifies FeLV proteins in the blood. These tests are both sensitive and specific and can identify cats with very early infections but in cats that appear healthy further testing may be needed to confirm the presence of the virus.

Exposure to infected cats will raise your cat’s risk of contracting FeLV. This is especially true for kittens and young adult cats. If your cat goes outside, fights with other cats, lives in a household where he or she is frequently exposed to new cats, or has close contact with other cats, you should speak to your vet about preventative measures you can take to protect your cat, such as vaccination.

Despite high transmission rates of FeLV, the prevalence of the disease has actually decreased over the last 25 years because of effective vaccines and reliable tests.  While this is positive news, the risk of infection is still a real threat in many regions throughout many countries, and it is therefore still important to test and vaccinate as advised by your vet who will be familiar with the local risk of infection.

Infected cats should be kept indoors to protect them from exposure to other diseases and reduce stress; they should also be neutered to prevent disease transmission to their offspring. Twice-yearly veterinary visits will help ensure FeLV-infected cats get the care they need.

Cats with persistent FeLV infection may live several years, but their overall life expectancy is decreased compared with uninfected cats.
Since persistently-infected cats can readily transmit infection to other cats they should be kept away from contact with other cats – especially young kittens and any unvaccinated cats.
Specifically in the United Kingdom, infection rates are now considered low at <1% of the population. Vaccination is considered a core vaccine for kittens, but non-core for adult cats. In other words beyond the first annual booster vaccine cats should be vaccinated according to their lifestyle. Those indoor cats not exposed to infected cats or those of unknown FeLV status will not typically need ongoing vaccination against this virus through adulthood although core vaccines against feline respiratory disease and paneleucopaenia are still advised

Keeping your cat indoors and away from other cats that might be infected with FeLV is one way to help protect your cat from contracting an infection. However, this may be impractical and for cats that go outdoors and may come into contact with other cats, effective FeLV vaccines are available. Your vet can help determine whether your cat should be vaccinated against FeLV.

Cats have been getting successfully vaccinated against FeLV for many years and while minor side effects do occur, the vaccines are usually well tolerated with a positive safety profile. Sometimes cats will experience adverse effects such as tenderness or swelling at the injection site, listlessness, or fever; these are usually transient and self-limiting. Adverse event reports of a more serious nature are genuinely rare reports. With appropriate targeting of the vaccine against those cats at risk, the overall disease control benefit significantly outweighs the potent risks associated with vaccination.Today some vaccines only require boosting every three years instead of annually, meaning that it is easier than ever to maintain your cat’s protection against FeLV.